论文部分内容阅读
Aim: The epidemic Influenza A/H1N1 in 2009 causes severe morbidity and mortality mainly in elder and children population.
Comparison of cellular and humoral immunity between Influenza A/H1N1/2009 infected patients and vacc
【摘 要】
：
Aim: The epidemic Influenza A/H1N1 in 2009 causes severe morbidity and mortality mainly in elder and children population.
【机 构】
：
Shanghai Institute of Immunology,Department of Immunology and Microbiology,Shanghai Jiaotong Univers
【出 处】
：
中国免疫学会第十届全国免疫学学术大会
【发表日期】
：
2015年10期
其他文献
B7-H3 is involved in regulation of tumor-associated macrophage polarization in hepatocellular carcin
B7 family members are aberrantly expressed on the human hepatocellular carcinoma (HCC) cell surface, and induce local and systemic immunosuppression.
目的：Cyclin D1作为细胞周期调控的关键因子，是肿瘤治疗的一个重要靶点。本研究在我们前期成功筛选和构建的肿瘤特异性抗Cyclin D1胞内抗体的基础上，进一步分析该胞内抗体对乳腺癌的体内外生长抑制作用，并结合差异蛋白质组学方法探讨其可能机制。
Protein kinase C iota (PRKCI) negatively regulates autophagy via AKT-mTOR signaling in U2OS osteosar
Objective: Protein kinase C (PRKC) is a family of serine/threonine kinases, and these PRKC isozymes have crucial roles in diverse cellular signaling processes including cellular proliferation, differe
目的：检测肺癌患者血清21种细胞因子的表达水平，分析其与肺癌临床病理特征的关系及各细胞因子间的相关性.方法：采用液相芯片技术检测经病理确诊但未治的40例肺癌患者及30例正常人血清中IL-2、IFN-γ、TNF-α、IL-12、IL-4、IL-5、IL-6、IL-10、IL-13、IL-17A、IL-8、ITAC、Fractalkine、MIP-3a、MIP-1a、 MIP1β、GM-CSF、IL-
microRNA let-7c is essential for anisomycin-triggered apoptosis of human leukemic cells by linking J
Anisomycin, an antibiotic produced by Streptomyces, strongly induces apoptosis in different histological sorts of cancer cells in vitro, superior dramatically to adriamycin.
TGF-β promotes colorectal cancer immune escape by upregulating B7-H3 and B7-H4 via miR-155/miR-143 a
Transforming growth factor-beta (TGF-β) suppresses T cell function to promote tumor immune escape.The essential roles of B7-H3 and B7-H4 have been uncovered in inhibiting T cell function during anti-t
Background: The Src homology 2 domain-containing tyrosine phosphatase 2 (SHP-2) has been reported to have both tumor-promoting and tumor-suppressing roles in tumorigenesis and tumor development.
在迎来肿瘤免疫治疗巨大机遇之时，我们必须保持清醒的头脑，客观的分析免疫治疗在肿瘤临床治疗中面临的挑战。肿瘤免疫治疗的复杂性 实体肿瘤的治疗是集手术、化疗、放疗、生物免疫治疗、中医药、心理治疗、营养代谢调整于一体的综合治疗。
Downregulated expression of GFRa1 promotes HCC progression though Epithelial-to-Mesenchymal Transiti
Background and Purposes: Accumulating evidences implies that the neurotrophic factor and their receptors contribute to tumor progression.
目的：本研究旨在探究和揭示肺癌患者恶性胸腔积液(MPE)免疫微环境中T淋巴细胞功能受损的免疫机制,为其免疫治疗提供新的线索。方法：流式细胞术检测35例肺癌患者MPE中单个核细胞及其配对的外周血单个核细胞(PBMC)中CD4+和CD8+T细胞的抑制性分子(Tim-3,PD-1,CTLA-4)及其功能性细胞因子(IFN-γ,GranzymeB)的表达。