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Background:Acute lung injury(ALI)is a common clinical syndrome,the pathogenesis is unknown,increased production of oxygen free radicals and antioxidant scavenging system imbalance is one of the main pathological changes.Glutamate transporter(EAATs)includes five subtypes(EAAT1-EAAT5),EAATs provides cysteine or glutamic acid for the synthesis of glutathione,preventing oxygen free radicals damage.