We expand the notion of Gaussian sequence model to n experiments and propose a re-fined Stein estimation which relies on pooling information across experiments.
With rapid accumulation of public gene expression data,meta-analysis to combine multiple transcriptomic studies for biomarker detection improves detection accuracy and robustness.
A solid tumor sample consists of mixed populations of cells,normal cells and cancer cells.Heterogeneity among cancer cells is further explained by multiple distinct tumor subclones.
This paper studies nonlinear cointegration models in which the structural coefficients may evolve smoothly over time,and considers time-varying coefficient functions estimated by nonparametric kernel
Large administrative data from healthcare claims and electronic health records provide significant opportunities for health services,drug safety,and other health research,due to large sample sizes and