2. 您的位置
3. 首页
4. 会议论文
5. Antinociceptive effects of fucoidan in rat models of vincristine-induced neuropathic pain

Antinociceptive effects of fucoidan in rat models of vincristine-induced neuropathic pain

来源 :The 6th FAONS Congress and 11th Biennial Conference of CNS(第 | 被引量 : 0次 | 上传用户：pwf890617

【摘 要】

：

Objective Chemotherapic drugs commonly induced peripheral neuropathic pain and limited its use in clinic.Fucoidan is an active constituent found in brown seaweeds,which have potential neuroprotection.

【作 者】

：

Chuan-yin Hu Ming-feng Xu Guo-ping Zhang Yin-run Ding Xiao-ping Chen 

【机 构】

：

Department of Biology,Guangdong Medical Colleg,Zhanjiang 524023,Guangdong,China

【出 处】

：

The 6th FAONS Congress and 11th Biennial Conference of CNS(第

【发表日期】

：

2015年3期

【关键词】

：

fucoidan vincristine neuropathic pain GABAB receptors 

下载到本地 , 更方便阅读

下载此文 赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

　　Objective Chemotherapic drugs commonly induced peripheral neuropathic pain and limited its use in clinic.Fucoidan is an active constituent found in brown seaweeds,which have potential neuroprotection.The present study was to evaluate the effect of fucoidan on the development of vincristine-induced neuropathic pain.

其他文献

Interaction between beta subunits and extracellular mat rix modulating sodium channels-involved mirr

Voltage-gated sodium(Nav)channels play key roles in induction,transmission,transduction of pathological pain.Nav channels are composed of a pore-forming α subunit and associated β subunits.

会议

Voltage-gated sodium channelsBeta subunitsMirror image painChondroitin sulfat

Role of sodium resurgent current in inflammatory pain

Sodium resurgent currents(resurgent currents)are non-conventional sodium currents that are activated during repolarization phase of action potentials.Activation of resurgent currents provides a depola

会议

sodium channelresurgent currentsDRGinflammatory mediatorpain

Pain and gain of Nav1.7 sodium channel

Nav1.7 is a critical player in pain sensation.Mutations of Nav1.7 have been found in a variety of chronic pain syndromes(e.g.,inherited erythromelalgia/IEM also known as “man of fire” syndrome)and per

会议

voltage-gated sodium channelNav1.7chronic painstructural modelinginherited e

Dopaminergic amacrine neurons are a key conduit of retrograde signaling in the retina

Latest evidence suggests that the retina is a two-way street: phototransduction can occur on either side of the retina,in the photoreceptor or ganglion cell layers,and then be transmitted to the other

会议

Dopamineamacrine cellneural circuitryretina

Signaling salient changes in the environment by human area V4(hV4)and surrounding areas

The human visual system can distinguish variations in image contrast over a much larger range than measurements of the static relationship between contrast and response in visual cortex would suggest.

会议

human V4 (hV4)contrastmotion coherenceadaptationsalient changesperception

Somatostatin receptor-mediated suppression of GABAergic synaptic transmission in cultured rat retina

Somatostatin(SRIF)is widely distributed in the central nervous system,which may modulate neurotransmitter release via activating the specific receptors(sst1-sst5).Our previous study showed that sst5 r

会议

Somatostatinsst5/sst2 receptorsspontaneous inhibitory postsynaptic currentscA

Orexin-A differentially modulates AMPA responses of ganglion cells and amacrine cells in rat retina

By activating their receptors(OX1R and OX2R)orexin-A/B regulate wake/sleeping states,feeding behaviors,but the function of these peptides in the retina remains unknown.

会议

orexin-AAMPA receptorneuromodulationganglion cellsamacrine cells

AT1 receptor blockade in the central nucleus of amygdala attenuates the effects of muscimol on sodiu

Evidence based on experimental animal studies indicates that the blockade of the GABAA receptors(GABAARs)in central nucleus of the amygdala(CeA)with muscimol reduces hypertonic NaCl and water intake b

会议

Sodium appetiteGABAA receptorAngiotensin type 1 receptorCentral nucleus of th

Application of recombinant adeno-associate virus to cat V1

The brain consists of many interconnected areas organized into complex networks.Accurately mapping of neuronal connectivity is fundamental for understanding how the brain processes information and gen

会议

cat V1adeno-associate virusoptogenetics

Cutaneous Neurogenic Inflammation at the Sensitized Acupoints induced by Gastric Mucosal Injury in R

In acupuncture practice,the most important step is to confirm the location of a sensitized acupoint which reflects a diagnosis and can be stimulated with a specialized needle to treat the disease.Abno

会议

Gastric Mucosal InjurySensitized AcupointsNociceptive NeuropeptideMast CellH