噻吩并噻吩及其稠合化合物在医药、农药、导电聚合物、笼形晶体、有机导体和超导体、感光受体、光电子材料、染料等方面有广泛的应用[1].目前,合成噻吩并噻吩并嘧啶酮类化合物的方法主要有以下三种:1)以含有异氰基噻吩衍生物为原料经分子内的环化缩合[2].
烯酮亚胺是应用于有机合成的重要反应中间体,常以CuAAC( Copper-catalyzedalkyne-azide cycloaddition)策略制备[1],以亲核试剂捕获,能高效构筑不同结构的杂环化合物[2].将该合成策略应用于分子内反应,可制备一系列环状化合物[3].
The delivery of a small-molecule agent into malignant tumors in a highly effective and highly selective way is a major challenge in successful chemotherapeutic intervention in cancer[1-3].
芳酰基甲酸是重要的有机合成中间体,广泛应用于药物、功能材料和精细有机化学品的合成等领域[1],近年来芳基甲酰甲酸作为一类新型的芳酰基化试剂引起了广泛关注.芳甲酰甲酸的普遍方法是利用高锰酸钾氧化苯乙酮类化合物来制备,但该方法高锰酸钾消耗量较大,易产生副产物和工业废水,同时后处理也较为繁琐,因此采用副产物少而且易于后处理的氧化体系来制备芳酰基甲酸化合物具有重要研究意义.
Cyclopropenes usually have high reactivity due to their significant strain in the small ring,which makes they become good three-carbon skeleton structure for synthesis.
Vicinal 1,2-diketones are important organic compounds with versatile reactivity in the synthesis of numerous chemical products.
腈类化合物是一类非常重要的有机合成中间体,广泛存在于天然产物、药物分子以及功能材料中,是一类重要的结构单元.近年来,非贵金属催化的碳氢官能团化反应由于其良好的原子经济性和反应区域选择性而被广泛应用于该类化合物的合成.
The allenes play an important role in organic chemistry and pharmaceutical research.
Fortunately,a particularly attractive photocatalysis strategy may provide a better alternative in organic synthesis because of avoiding additional ligands,bases or elevated temperatures.
An efficient synthesis of biphenyls via three-coordinate planar dinuclear Cu2(ophen)2 [1] complex catalyzed homocoupling of arylboronic acids under air condition and in the absence of any base was dem