【摘 要】
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Invariant natural killer T(iNKT) cells are regulatory T cells that play an important role intumor immunity,regulating immune responses and preventing autoimmuni
【机 构】
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CollaborativeInnovationCenterofHenanProvinceforGreenManufacturingofFineChemicals,KeyLaboratoryofGree
论文部分内容阅读
Invariant natural killer T(iNKT) cells are regulatory T cells that play an important role intumor immunity,regulating immune responses and preventing autoimmunity.1 α-galactosylceramide,a synthetic α-galactosyl ceramide,presented by CD1d,can activate iNKTcells to exhibit powerful immunostimulation.2 Phosphate groups play an important role inmedicinal chemistry with important structural characteristics and properties.3 The introduction ofphosphonic ester groups can significantly change the physical and chemical properties of parentmolecule,and has brought fundamental changes in intermolecular forces and molecular polarity.
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