Development of an advanced deformable phantom to analyze the dose difference by respiratory motion:D

来源 :The 15th Asia-Oceania Congress of Medical Physics (AOCMP2015 | 被引量 : 0次 | 上传用户:a1lan
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
  Purpose The difference between three-dimensional(3D)and four-dimensional(4D)dose is effected by factors such as tumor size and motion amplitude.To propose quantitative results about the effect by these factors,a phantom that can be possible for systematic analysis through independently controlling each factor is essential.The purpose of this study is to develop the 4D deformable lung phantom which has the above the performance and evaluate the phantoms characteristics.Method The phantom was designed in the structure that sponge including silicon tumor was inserted into acrylic cylinder simulating the lung cavity.To simulate precise and various size tumors,tumors were made by pouring liquid silicon to molds manufactured by 3D printer.Diaphragm motion was simulated in the range of amplitude from 1 to 8 cm with various breathing period using piston and programmable motor.To evaluate the characteristics of phantom,four-dimensional computed tomography image of phantom were acquired.Trajectories of tumor center-of-mass was evaluated,and diaphragm-tumor motion correlation curve was acquired through evaluating the correlation between diaphragm motion and tumor excursion for adjusting tumor motion amplitude.To quantitatively analyze the difference between 3D and 4D dose according to tumor size and motion amplitude,3D dose on the basis of internal target volume-based plan and 4D dose were calculated.Results The trajectories of tumor mainly were superior-inferior(SI)direction.Diaphragm-tumor motion correlation curve showed increasing tumor excursion of SI direction according to increase of diaphragm motion.The discrepancy of differences between 3D and 4D dose was found when the each factor is varied.Conclusion This phantom can control tumor size and motion amplitude independently and contribute quantitative analysis of the difference between 3D and 4D dose and has the potential applications for evaluating deformable registration accuracy and improving accuracy when treatment for which internal organ motion exists is planned.
其他文献
Introduction:We have developing a collision-detection simulator between treatment units and a patient for dynamic wave arc(DWA)irradiation achieving dose delivery to a target by continuous ring and ga
Objective:To analyze three different kinds of finger shape ionization chamber of medical linear accelerator is used the response of the dose rate.Methods:Choose three different kinds of finger shape i
Purpose:This study was to evaluate the setup accuracy of intensity modulated radiation therapy(IMRT)of ten patients with lung cancer by cone-beam computed tomography(CBCT)in Elekta Synergy S Linear Ac
Purpose:The leakage and transmission rate(LTR)of the new-type multileaf collimator(MLC)in the Elekta Synergy-S accelerator was measured,the effects of the X-ray energy and gantry angles on the LTR,as
Purpose:A fiber-optic radiation sensor using Cerenkov radiation has been widely studied for use as a dosimeter for proton therapeutic beam.Although the fiber-optic radiation sensor has already been in
会议
Purpose:To assess the benefit of using bladder wall sub-volume equivalent uniform dose(EUD) constraints in prostate cancer IMRT planning.Methods and Materials:Two IMRT plans,with and without EUD const
Purpose:Pencil beam dose calculation algorithm(PBDCA),due to its efficiency and robustness,has been widely used in most commercial treatment planning systems(TPS).The purpose of this study is to devel
Objective:To study acute radiation-induced small bowel damage in patients with abdominal-and-pelvic tumor radiation therapy,in order to explore the clinical and dosimetric factors associated with grad
Objective The paper is to perfect complete the QA process by developing of the method used to fast verify the center position of body patient which are treated with Cynthia Gamma Knife.method The rese
Purpose:Radiation therapy oncology group(RTOG) 0631 suggest different planning method in spine stereotactic body radiation therapy(SBRT) according to location of cancer owing to its distinct shape.The
会议