βCaMKⅡ overexpression impairs long-term depression of dentate gyrus and behavioral flexibility

来源 :The 6th FAONS Congress and 11th Biennial Conference of CNS(第 | 被引量 : 0次 | 上传用户：hlf00852

【摘要】

：

【作者】

：

Pengcheng Yin Qi Wang Xiao-Hua Cao

【机构】

：

Shanghai Institute of Brain Functional Genomics,Key Laboratories of MOE and STCSM,East China Normal

【出处】

：

The 6th FAONS Congress and 11th Biennial Conference of CNS(第

【发表日期】

：

2015年3期

【关键词】

：

βCaMKⅡ dentate gyrus long-term depression behavioral flexibility

下载到本地 , 更方便阅读

下载此文赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

　　Objective Calcium/calmodulin-dependent protein kinase Ⅱ(CaMKⅡ)plays an important role in synaptic plasticity,learning and memory.The α and βCaMKⅡ are two main isoforms of CaMKⅡ in the forebrain.The roles of αCaMKⅡ in synaptic plasticity have been studied extensively; however,the information regarding that of βCaMKⅡ is rare.

其他文献

Decreased 5-methylated cytosine(5-mC)content of genome was induced in dopaminergic neurons in the su

Parkinsons disease(PD)is a progressive neurodegenerative disease related to aging,and is due to the degeneration and death of dopaminergic neurons in the substantia nigra pars compacta(SNc)of the vent

会议

Parkinson's diseaseneurotoxicitygenome5-methylated cytosine

Learning-based stable memory

During memory formation,granular cortex is reconstructed by re-learning the same or similar tasks.The effect of repetition learning is thought to reflect a progressive optimization of memory structure

会议

stable memoryinformation granulelearninggranularity

Expression of the Cβ catalytic subunit of protein kinase A in the lateral dorsal thalamic nucleus of

会议

Local infusion of Ghrelin into basolateral amygdala blocks CTA memory formation in rats

会议

The plasticity of trigeminal motor nucleus in unilateral mastication model rats

Objective Unilateral mastication,an abnormal chewing habit,caused by effects such as unilateral molarless,muscle and joint dysfunction.There are many patients still remain hemi mastication habits afte

会议

trigeminal motor nucleusH-reflexextra cellular recordingunilateral masticatio

Targeting unconditioned stimulus-induced memory reactivation to prevent nicotine relapse

会议

nicotinerelapsememoryunconditioned stimulusreactivation

Circuit mechanism for perceptual memory-in vivo verification of Hebb cell assembly hypothesis

会议

temporal sequencelearning and memoryprimary visual cortexoptogeneticsneurona

Default mode network study on the brain of musical composers

会议

composerDMNICA

Fear erasure facilitated by inhibitory neuron transplantation