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In recent years, fingerprint profiling has been shown to be an effective method for the standardization and quality control of traditional Chinese medicines.To the best of our knowledge, the feasibility of using electrophoretic techniques for the standardization and quality control of various traditional Chinese medicines based on the fingerprint profiling of polysaccharides has not been reported.This is not surprising since the separation and detection of carbohydrates, especially long-chain polysaccharides, is well known to be a highly challenging and difficult analytical problem.