The in situ Organization of Calsequestrin Strings in Rat Heart Sarcoplasmic Reticulum and its Functi

来源 :2016年国际生理学学术大会 | 被引量 : 0次 | 上传用户:information1005
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
  The Ca2+spark is the basic unit of Ca2+release in the sarcoplasmic reticulum(SR).The couplon structure integrity is the basis for the Ca2+-induced Ca2+release(CICR).Whether and how calsequestrin(CSQ)organization affects Ca2+sparks are still unknown.
其他文献
Objective:Renin-angiotension system is known to induce the development of atrial fibrillation through atrial structural and electrical remodeling.small conductance calcium-activated potassium channels
Vascular remodelling has been found to be one of the most important factors in the occurrence of post-spaceflight orthostatic intolerance,and inflammatory response might play an important role in the
Objective: To explore the regulative mechanism with β-adrenergic receptor on hemodynamics of anesthetized rats in acute hypoxia,the pulmonary vascular resistance(PVR)and total peripheral resistance(TP
Ojective:Hypertension is a independent risk factor of atrial fibrillation(AF).however,the efficacy of an angiotensin Ⅱ receptor blocker for the prevention Occurrence of atrial fibrillation in hyperten
Angiotensin-(1-5)[Ang-(1-5)],which is a metabolite of Angiotensin-(1-7)[Ang-(1-7)] catalyzed by angiotensin-converting enzyme(ACE),is a novel vasoactive pentapeptide of the renin-angiotensin system(RA
To clarify the role of β3-AR in rat thoracic aorta contractility and the underlying mechanisms.Rats were randomly divided into control and SR(SR 59230A)groups.BRL 37344(BRL)was used to detect the role
The renin angiotensin system(RAS)is a current target in the treatment of hypertension and end-organs damage.The present study was designed to investigate the effects of aliskiren,a direct renin inhibi
Aim: To investigate the protective effect and the mechanism of simvastatin on myocardial injury caused by diabetes with acute hypoglycemia.Methods: We used STZ to make the model of diabetes,and insuli
Introduction: Cyclins/retinoblastoma protein(pRb)pathway participates in cardiomyocyte hypertrophy.Cyclins and cyclin kinase contribute to the activation of cyclin/Rb signal pathway.MicroRNAs(miRNAs)w
External lateral parabrachial nucleus(elPBN)within the pons and rostral ventrolateral medulla(rVLM)contribute to central processing of excitatory cardiovascular reflexes during stimulation of cardiac
会议