Effects of PEG conjugation on protein stability and bioactivity:modulation of PEG size,structure and

来源 :The 5th Sino-US joint Conference of Chemical Engineering(第五届 | 被引量 : 0次 | 上传用户:cw545400
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  PEG-drug conjugates have several advantages over their parent protein molecules, such as prolonged residence in body,decreased degradation by metabolic enzymes and reduction or elimination of protein immunogenicity.Thanks to these favorable properties, PEGylation now plays an important role in drug delivery, enhancing the potentials of peptides and proteins as therapeutic agents[1].
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