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Objective The purpose of this study is to evaluate the prevalence and characteristics of myocardial bridging (MB) in a large series of patients and to assess the relationship between atherosclerosis and MB by using the dual-source computed tomographic coronary angiography.Methods Dual-source CT coronary angiography were performed on 1220(754 males, 466 females) cases of routine physical or clinical diagnosis of coronary artery disease.Using MPR, MIP, VRT and the other image processing technique for image post-processing and then to observe the detection rate, position, length and depth of myocardial bridge.The patients were divided into 2 groups according to with or without coronary artery disease in 2 cm proximal and distal of myocardial bridge and to compare the age of onset, the length and depth of MB between 2 groups.Results Among these 1220 patient, 622(50.98%) patients were found with parietal coronary arteries(694segments) and 614 (98.71%) segments were at the LAD.The average length is 28.6mm, and the average depth is 2.3mm.All the MBs were without obvious coronary artery atherosclerosis and 319 cases with coronary artery atherosclerosis 2cm near MBs were found, including 298 cases (42.94%) in proximal and 21 cases(3.03%) in distal.The depth and length between the 2 groups of MB were no significant difference (P>0.05).Conclusions The detection rate of DSCT on myocardial bridge is high.DSCT is the optimal noninvasive method that can clearly show the location, length and depth of myocardial bridges, and the relationship with neighboring coronary artery.