【摘 要】
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Molecular designs that afford tunable supramolecular assemblies are of interest in a variety of applications,including catalysis,sensing,drug delivery,tissu
【机 构】
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DepartmentofChemistry,UniversityofMassachusetts,Amherst,MA01003,USA
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Molecular designs that afford tunable supramolecular assemblies are of interest in a variety of applications,including catalysis,sensing,drug delivery,tissue enginerering and diagnostics.When these assemblies are nanoscopic in size and are responsive to specific stimulus,then the interests in these nanoscale scaffolds are even higher.We have developed macromolecule-based amphiphilic supramolecular assemblies,which not only exhibit these features,but also can bind guest molecules efficiently.We have also shown that these non-covalently bound guest molecules can be released in response to specific triggers.The molecular design principle is versatile enough to be adapted for physical,chemical,or biological stimuli.From a fundamental perspective,we divulge the structural factors that underlie the stimuli-responsive behavior of supramolecular assemblies.From an application perspective,the implications are numerous.
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