【摘 要】
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Background.The purpose of this study was to determine the features of the eldedy patient with nasopharyngeal carcinoma (NPC).Methods.The medical records of 212 patients with NPC, aged >65 years, and r
【机 构】
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Department of Radiation 0ncology, Cancer Hospital, Chinese Academy of Medical Sciences and Peking Un
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Background.The purpose of this study was to determine the features of the eldedy patient with nasopharyngeal carcinoma (NPC).Methods.The medical records of 212 patients with NPC, aged >65 years, and receiving radiotherapy were retrospectively reviewed.Comorbidity was rated using the Charlson Comorbidity Index (CCI).Results.Twenty-four patients (11.3%) scored >3 and 188 patients (88.7%) scored <3 rated by CCI.The median actuarial irradiated dose of the nasopharynx was 72 Gy (range, 20-94 Gy) with 87.3% patients receiving >70 Gy.0ne hundred fifty-four patients had stage Ⅲ/Ⅳ disease.The actuarial local control, cancer-specific survival (CSS), and overall survival (0S) rates at 5 years were 68.8%, 63.5%, and 47.0%, respectively.0n multivariate analysis, stage (hazard ratio [HR], 1.489;95% confidence interval [CI], 1.168-1.897;p =.001), the technique of radiotherapy (HR,0.674;95% CI, 0.476-0.953;p =.025), and anemia (HR, 3.081;95% CI,1.624-5.845;p =.001) were independent prognostic factors.Conclusion.The elderly patients with NPC may inherently predict poor outcomes.
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