【摘 要】
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We examined the changes in blood flow in the femoral artery caused by botulinum toxin A in rats.Blood flow was measured using laser Doppler flowmetry.We used male Sprague-Dawley-derived rats weighing
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We examined the changes in blood flow in the femoral artery caused by botulinum toxin A in rats.Blood flow was measured using laser Doppler flowmetry.We used male Sprague-Dawley-derived rats weighing between 350 and 400 g.The study was performed on 6 groups; each of them consisted of 30 rats (control and botulinum toxin A 0.5, 1,2, 4, and 8 units).The laser Doppler flowmetry revealed that blood flow in the femoral artery increased by the third day in the groups injected with 1 or more units of botulinum toxin A.In the groups injected with 8 units of botulinum toxin A, we recognized an increase of blood flow from the second day.Our results suggest that botulinum toxin A is concerned in improving blood flow.
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