Synthesis of o-Chloroaniline Derivatives via Tertiary Amines,Arynes,and Carbon Tetrachloride

来源 :中国化学会第十六届全国有机合成化学学术研讨会 | 被引量 : 0次 | 上传用户：hdw1978

【摘要】

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【作者】

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Sheng-Jun Li Shi-Kai Tian

【机构】

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Department of Chemistry,University of Science and Technology of China,Hefei,Anhui 230026,China

【出处】

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中国化学会第十六届全国有机合成化学学术研讨会

【发表日期】

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2019年3期

【关键词】

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o-Chloroaniline Derivatives Tertiary Amines Arynes Carbon Tetrachloride

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　　We have successfully developed a new method for synthesis of o-chloroaniline derivatives by three-component reactions of tertiary amines,arynes and carbon tetrachloride.With 2-(trimethylsilyl)aryl triflates as aryne precursors,a range of tertiary amines smoothly reacted with arynes and carbon tetrachloride to afford structurally diverse tertiary o-chloroaniline in moderate to excellent yields with mild conditions and without transition metals.

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Synthesis of o-Chloroaniline Derivatives via Tertiary Amines,Arynes,and Carbon Tetrachloride

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