醌类化合物广泛存在于天然产物、药物分子以及生物活性分子中,是许多中草药(何首乌,紫草,芦荟,丹参等)的有效成分,具有很好的药用价值.我们发现邻炔基苯乙酮与二甲亚砜在铜催化体系下,可以顺利地进行分子内的环加成反应和硫甲基化反应,一锅法合成出α-萘醌类化合物.该反应具有条件温和,操作简单等优点.
含杂原子芳香环化合物由于在药物和材料科学领域中的广泛应用,受到化学科学者的广泛的关注.杂合吡喃化合物普遍存在于各种天然产物、药物中,是一种重要的化学中间体.
Aryl sulfides are an important type of structural unit,widely presented in bioactive pharmaceuticals,and also materials.Aryl sulfides are important synthetic intermediates and chiral ligands in organi
炔烃选择性还原为顺式烯烃在有机合成中是很重要的一个步骤,特别是在一些重要的高价值化合物合成中(例如生物活性分子、天然产物以及工业材料等),高纯顺式烯烃的合成是关键步骤.
1,7-diazaspiro[4.4]nonaneanalogues could serve as an importantstructural unit in many bioactive natural products,pharmaceuticalsas wellas agricultural chemicals.
Transition-metal-catalyzed,particularly functionalization of C-C and C-H bonds via employing cheap and low toxic copperas the catalyst for the construction of C-N bonds has attracted much attention in
In recent years,the Pd-catalyzed intermolecular asymmetric allylic alkylation of indoles has attracted considerable attention from the synthetic community.
Thiophene-based materials are a very important class of organic materials because of their biological,electronic,magnetic,and optical properties.
A diverse library of novel quinazoline ketone carbamates were synthesized by copper-catalyzed cross coupling between quinazoline 3-oxides and various formamides.
The conversion of greenhouse carbon dioxide(CO2) as a renewable C1 synthon into value-added chemicals,such as cyclic carbonates,represents one of the hot topics in catalysis field.