Novel Insights into the Strengths and Limitations of Current Strategies to Prevent Exercise-Mediated

来源 :2013第三届内分泌与代谢大会暨2013第二届糖尿病大会 | 被引量 : 0次 | 上传用户:jiji19860729
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  Despite its many health benefits, exercise in type 1 diabetes mellitus increases the risk ofhypoglycaemia and associated health hazards, thus discouraging many diabetic individuals from adopting an active lifestyle.In recent years, we have evaluated the efficacy of several strategies to reduce such a risk,namely exercise timing, short bout of intense exercise, and the use of continuous glucose monitoring systems (CGMS).Using hyperinsulinaemic-euglycaemic clamp methodologies we have shown that exercising late in the afternoon increases glucose requirements to maintain euglycaemia both immediately after exercise and during sleep time, whereas no such an increase in glucose demands occurs during night time when exercise is performed early in the afternoon.
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