Personalized medicine targets individualized treatment and care based on personal and genetic variation.It focuses on the best ways to develop new therapies and optimize prescribing by steering patients to the right drug at the right dose at the right time.However, in order to achieve the goals of personalized medicine, many obstacles must be resolved, which include scientific challenges, such as determining which genetic markers have the most clinical significance and conducting clinical studies to identify genetic variation that are correlated with a drug response.It is already known that genetic variation frequencies occur with varying prevalence in populations of different ethnic or geographic origins.Therefore, it is essential to conduct a genetic variants analysis in various populations.Based on the own work in Bio-X Institutes, am going to present our thoughts and strategies for study of personalized medicine in this important meeting.