Pyridine nucleotides including NAD(H) and NADP(H), are essential compounds in all living organisms and well-known as electron-transferring coenzymes in many redox reactions.Moreover, all organisms require continued NAD(P)(H) replenishment due to the existence of NAD-consuming enzymes, which break the glycosidic bond between nicotinamide (NIM) and the ADP-ribose moiety.