Collaborative Matrix Factorization for Predicting Drug-Target Interactions

来源 :2014数学、计算机与生命科学交叉研究青年学者论坛 | 被引量 : 0次 | 上传用户:bang67640
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We address the problem of predicting new drug target interactions from three inputs: known interactions,similarities over drugs and over targets.This problem has been considered by a lot of methods recently which however have a common drawback that prediction is done by two independent directions, one being from drugs and the other from targets, resulting in that drug-target "interactions" cannot be captured thoroughly.
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