Relationship between atherosclerotic plaque characteristics and extracellular matrix metalloproteina

来源 :第十二届中国介入心脏病学大会(CIT2014) | 被引量 : 0次 | 上传用户:caiguoxi
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Background The main mechanism of acute coronary syndrome (ACS) is coronary plaque rupture and secondary thrombosis.There are many factors involved in plaque rupture,such as inflammation,blood rheology,vascular wall stress,vasoconstriction,plaque stability.Matrix metalloproteinases (MMPs) in coronary atherosclerotic plaques,especially in unstable plaque activity was significantly increased,is the main reason leading to clinical coronary events.
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