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5. A Multifunctional Fluorescent Chelator for Targeting Metal-Induced Aβ Aggregation

A Multifunctional Fluorescent Chelator for Targeting Metal-Induced Aβ Aggregation

来源 :第九届全国无机化学学术会议 | 被引量 : 0次 | 上传用户：ythaohaizi

【摘 要】

：

Alzheimers disease(AD)is the most common form of dementia.Amyloid β(Aβ),a peptide of 40 or 42 amino acids,plays a key role in AD pathology.The aggregation of Aβ is one of the neuropathological hallmar

【作 者】

：

Tao Yang Jian Luo Liu Yang Cheng Yao Xiaohui Wang 

【机 构】

：

College of Sciences,Nanjing Tech University,Nanjing,211816

【出 处】

：

第九届全国无机化学学术会议

【发表日期】

：

2015年7期

【关键词】

：

Aβ Aggregation Fluorescent Chelator Theranostic Agent 

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　　Alzheimers disease(AD)is the most common form of dementia.Amyloid β(Aβ),a peptide of 40 or 42 amino acids,plays a key role in AD pathology.The aggregation of Aβ is one of the neuropathological hallmarks of AD.While the aggregates,especially soluble oligomers,spark the neuronal dysfunction and cell death.

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