Muscadine grapes and blueberries are natural sources of polyphenolic compounds.The aim of the study was to investigate whether the polyphenolic compounds of blueberry and muscadine could inhibit the growth of two major foodborne bacterial pathogens,Salmonella Enteritidis and Listeria monocytogenes.Spray-dried blueberry water extract,blueberry alcohol extract,muscadine water extract and muscadine wine extract were suspended,individually in sterile distilled water at 1% (w/v),and were sterilized by passing each through a 0.2 l in syringe filter.Each polyphenolic suspension was mixed with an equal volume of double strength tryptic soy broth (TSB).