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Pituitary adenoma(PA),tumor occurring in the pituitary gland,is one of the most common intracranial adenomas.Although PA is usually benign and non-metastatic,it can result in serious disorders such as infertility,hypertension and diabetes mellitus.35％of PA can invade the dura mater,cranial bone and sphenoid sinus,which may lead to cerebrospinal or systemic metastasis(pituitary carcinoma).