{2-[1-(3-Methoxycarbonylmethyl-1 H-indol-2-yl)-1-methyl-ethyl]-1Hindol-3-yl}-acetic acid methyl este

来源 :首都医科大学2013年研究生学术论坛 | 被引量 : 0次 | 上传用户:weishuren33
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  {2-[1-(3-Methoxycarbonylmethyl-1H-indol-2-yl)-1-methyl-ethyl]-1H-indol-3-yl}-acetic acid methyl ester (MIAM) was provided as a DNA-intercalator.For the comprehensive evaluation of this new intercalator, an assay system consisting of cell, S180 mouse, healthy mouse, spectrum, non-spectrum, and gel electrophoresis models was constructed.On the cell (S180, K562, MCF-7, HeLa and HepG2) models, MIAM selectively inhibited the viability of HeLa.
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