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Purpose To identify the correlation of cardiac function and ventricular strain assessed on cardiac MRI cine images with hemodynamics of right heart catheterization in patients with connective tissue disease associated pulmonary artery hypertension. Methods After informed consent, 25 patients (age, 35.1±11.0years; male/female=2/23) with right heart catheterization proved connective tissue disease associated pulmonary artery hypertension (SLE/pSS/SSc/overlap=12/2/1/10; mPAP, 45.0±16.1mmHg) were included. Cardiac MRI (3.0T, Magnetom Skyra Siemens, Germany) was performed before treatment was given. Cardiac function was measured on cine images using Argus software (Siemens, Germany). Ventricular deformation was measured as the average total peak systolic strain in longitudinal, radial and circumferential direction on cine images using cvi42 software (version 5.3, Circle Cardiovascular Imaging, Canada). Spearman correlation was used. Results Longitudinal strain of the RV correlated with sPAP (r=0.635, P=0.020), dPAP (r=0.718, P=0.006), mPAP (r=0.718, P=0.003) and PVR (r=0.693, P=0.001). Radial strain of the RV correlated with sPAP (r=-0.682, P=0.010), dPAP (r=-0.753, P=0.003), mPAP (r=-0.685, P=0.001) and PVR (r=-0.680, P=0.002). Circumferential strain of the RV correlated with sPAP (r=0.559, P=0.047) and dPAP (r=0.555, P=0.049). There was no significant correlation between right heart catheterization results with strain of the left ventricle. There was no significant correlation between right heart catheterization results with EDV or EF of the LV or RV. Conclusion RV strain measured on cardiac MRI cine images correlates with right heart catheterization results in patients with connective tissue disease associated pulmonary artery hypertension, and is promising to reflect the degree of right ventricular afterload and identify early cardiac dysfunction.