【摘 要】
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TACE is one of the most well studied enzymes in the ADAM family, and has been found to be re-sponsible for the releasing of around 80 proteins from their membra
【机 构】
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InstituteofMolecularBiology,CollegeofMedicalScience,ChinaThreeGorgesUniversity,Yichang,China
【出 处】
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8th IUPAP International Conference on Biological Physics(第八届
论文部分内容阅读
TACE is one of the most well studied enzymes in the ADAM family, and has been found to be re-sponsible for the releasing of around 80 proteins from their membrane-bound forms, such as TNF-α, TGF-β, TNF receptor I, TNF receptor Ⅱ, interleukin-6 receptor, L-selectin, and Notch.But how TACE recognizes the cleavage sequence of these proteins remains an unsolved question.
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