【摘 要】
：
Coumarins and flavones are well-known natural product classes in drug discovery,arylimidazo[1,2-a]pyridine is also a privileged structure in some marketed d
【机 构】
：
Pharmacyschool,JiangsuUniversity,Zhenjiang212013
【出 处】
：
中国化学会第十三届全国有机合成化学学术研讨会
论文部分内容阅读
Coumarins and flavones are well-known natural product classes in drug discovery,arylimidazo[1,2-a]pyridine is also a privileged structure in some marketed drugs,therefore,the synthesis of their derivatives have attracted considerable attention in pharmaceutical industry in order to find out some new biological activities out of these derivatives.Herein,we have developed a series of simple synthetic approaches for generating different derivatives of coumarins,flavones and arylimidazo[1,2-a]pyridines via radical process and sulfenylation methods,most reactions proceeded under relatively environmentally friendly reaction conditions with high selectivity in moderate to good yields.
其他文献
Transfer hydrogenation (TH) constitutes a fundamental tool in organic synthesis,which appeals to many synthetic chemists because it does not need for flamma
In recent years,iron salts,being effective,alternative,and promising transition-metal catalysts,have received much more attention because of their low cost,
二氧化碳不仅是温室气体的主要成分,同时也是一种可再生的C1资源,具有廉价易得、无毒、不可燃等优点。因此,将二氧化碳替代化石燃料通过构建C-N键、C-O键和C-C键的方式转
由二级碳正离子转化为一级碳正离子的反马尔科夫尼科夫重排还没有文献报道过。在我们近期关于硫元素引导的烯丙位碳氢键官能化反应的研究过程中(Fig 1)[1]，偶然观察到的经
Over the past decades,N-heterocyclic carbenes (NHCs) have developed into a powerful kind catalysts for organic syntheses.Thus numerous efforts have been to
In the last years,we have carried out the studies on the silver-catalyzed reactions of isocyanides,and discovered a series of novel reactions,including the
The recent developments in inert chemical bond activation have emerged as very attractive altematives to the traditional cross-coupling reactions.With the a
Ni-catalyzed reductive cross-coupling of alkyl halides with other electrophiles has provided facile protocols to the construction C-C bonds,featuring excell
More recently,Yu group disclosed the first Pd-catalyzed C(sp3)-H functionalization of aldehydes and ketones using transient directing group(TDG) strategy.He