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  5. Role of GSK3β in Maintaining Germ Cell Survival during Meiotic Prophase Ⅰ in mice fetal ovary

Role of GSK3β in Maintaining Germ Cell Survival during Meiotic Prophase Ⅰ in mice fetal ovary

来源 :2016年国际生理学学术大会 | 被引量 : 0次 | 上传用户：liongliong453
【摘 要】
：
Female mammalians have a limited reproduction lifespan,since germ cells are generated merely during fetal life,then followed by continues depletion during adult life.Thus,research on mechanisms regula
【作 者】
：
Jia Wen Chao Wang Guoliang Xia 
【机 构】
：
State Key Laboratory of Agrobiotechnology,College of Biological Sciences,China Agricultural Universi
【出 处】
：
2016年国际生理学学术大会
【发表日期】
：
2016年6期
【关键词】
：
GSK3β meiosis DSBs repair germ cell loss 
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　　Female mammalians have a limited reproduction lifespan,since germ cells are generated merely during fetal life,then followed by continues depletion during adult life.Thus,research on mechanisms regulating fetal germ cells maintaining and survival may help female with infertility or subfertility problems.Glycogen synthase kinase-3 beta(GSK3β)has been detected in various signaling pathways,involved in controlling cell proliferation,differentiation,survival and apoptosis.
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