Peptide Amphiphiles as Carriers for Integrin Targeted Drug Delivery

来源 :纳米药物及纳米生物技术国际学术大会暨中国药学会纳米药物专业委员会成立大会 | 被引量 : 0次 | 上传用户:bingying888
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
Amphiphilic molecules are designed using peptides as targeting moiety and alkyl group as lipophilic segment of molecules.These molecules self-assemble to form micelles in an aqueous environment with peptide targeting moiety arranging at the surface of micelles and alkyl group forming a lipophilic core.
其他文献
Nanoparticles of various compositions and structures and with sizes below 150 nm are the subjects of intensive investigation for the effective intracellular delivery of diagnostics and therapeutics.
会议
Our research interests focus on the study of cancer cell communications by microfluidics and the development of nanotechnology to detect and destruct cancer cells.Recent studies reveal that solid tumo
会议
High-performance fluorescent materials for cancer targeting are highly desirable for biosensing and imaging in vivo.Here we report a unique molecular design strategy for tailoring the aggregation-indu
会议
In this work, poly(ethylene oxide)-b-poly(N-methacryloyl-N-(tert-butyloxycarbonyl)cystamine)(PEO-b-PMABC) diblock copolymers were developed by reversible addition-fragmentation chain transfer (RAFT) p
会议
Magnetic resonance imaging (MRI) probes are the important tools for discovering small pathological changes with functionality analysis.Probe structural design, functionality,multimodality, and applica
会议
Aptamers are single-stranded nucleic acids having molecular recognition properties similar to antibodies, and isolated by in vitro selection and amplification process, SELEX.Aptamer engineering includ
会议
Many aromatic and planar mutagens can inhibit both transcription and replication of DNA and cause cytotoxicity and mutations by intercalating into the base pairs of DNA.To date, perylene derivatives h
会议
While thermo-chemotherapy has proved to be effective in optimizing the efficacies of cancer treatments, traditional chemotherapy is subject to adverse side effects and heat delivery is often challengi
会议
Fluorescent imaging in the second near-infrared window (NIR-Ⅱ, 1.0~1.4 μm) is appealing due to minimal autofluorescence and negligible tissue scattering in this region, affording maximal penetration d
会议
Nano-scaled drug delivery systems have been attracting great attention in cancer treatment.However, the abnormal blood supply and highly heterogeneous microenvironment of tumor bring tremendous diffic
会议