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  5. Synergistic Anticancer Effects of Triptolide and Celastrol, Two Main Compounds from Thunder God Vine

Synergistic Anticancer Effects of Triptolide and Celastrol, Two Main Compounds from Thunder God Vine

来源 :第十四届全国中药和天然药物学术研讨会暨第十三届中药全球化联盟大会 | 被引量 : 0次 | 上传用户：shaoqing5320
【摘 要】
：
Objective Triptolide and celastrol are two most widely studied and promising compounds isolated from Thunder God Vine (Trypterigium wilfordii Hook.f.) with promising anticancer activity.However,their
【作 者】
：
Kejun Cheng Qiwei Jiang Xu Zhang Zhi Shi nd Xing Wei 
【机 构】
：
Lishui Institute of Agriculture Sciences, Lishui;Fudan University, Shanghai;National First-Class Key
【出 处】
：
第十四届全国中药和天然药物学术研讨会暨第十三届中药全球化联盟大会
【发表日期】
：
2014年8期
【关键词】
：
Triptolide Celastrol Combination therapy Cancer 
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Objective Triptolide and celastrol are two most widely studied and promising compounds isolated from Thunder God Vine (Trypterigium wilfordii Hook.f.) with promising anticancer activity.However,their clinical application was limited by toxicity.We aim to investigate the synergistic anti-proliferative effects of triptolide with celastrol in cancer and the molecular mechanism.
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