Background: High-throughput sequencing has become a basic source of bioinformatics data analysis.Better high-throughput sequencing methods continue to emerge and the data generated in a single sequencing is still increasing.Existing data management methods or software are basically designed for the Sanger sequencing data, which are far behind and unable to fit with large-scale sequencing data.Therefore, we need a database management program for large-scale high-throughput sequencing data.