Tunable Cascade Reactions of Alkynols with Alkynes Using a Combination of Sc(OTf)3 and Rhodium Catal

来源 :中国化学会全国第十二届有机合成化学学术研讨会 | 被引量 : 0次 | 上传用户:wangzixiaoxun
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  Transition metal-catalyzed cascade transformations of alkynols have recently attracted extensive interest because they allow highly efficient synthesis of oxygen-containing heterocyclic compounds,including natural products and drugs.Most of these reactions are catalyzed by tungsten,gold,platinum,palladium,and copper catalysts,which involve intramolecular cycloisomerization of alkynols together with diverse transformations such as Prins-type cyclization,Diels-Alder reaction,and Povarov reaction.However,cascade reaction of alkynols involving C-H activation has not been reported.
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