The ERK activation in the local interneurons of spinal dorsal horn is critical for histamine induced

来源 :The 6th FAONS Congress and 11th Biennial Conference of CNS(第 | 被引量 : 0次 | 上传用户:liqiang915
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
  Objective Itch has a significant negative impact on an individuals quality of life.However,the molecular mechanisms underlying itch processing in the spinal cord remain largely unknown.Methods pERK staining was used to reveal the activation of ERK in the spinal cord in mice treated with pruritogens.
其他文献
Recent studies have shown that neurons in the dorsal medial superior temporal area(MSTd)signal the direction of self-translation in response to both optic flow and inertial motion.However,the neural t
Objective: Sensory input drives cortical circuit formation during development.Dark reared mice showed a significant decrease of miniature excitatory postsynaptic current(mEPSC)frequency in visual cort
Traumatic brain injuryas a cause of progressive neurodegenerative disorders and display Alzheimers disease(AD)-like cognitive impair-ments.There is solid evidence that traumatic brain injury(TBI)is a
The arrival of action potential(AP)at presynaptic terminal usually cause immediate synchronized release(SR)of neurotransmitter and postsynaptic response within a time window of 1-2 ms.
In previous studies,we have found that the GluN2B-containing NMDA(NMDA-GluN2B)receptors-mediated long-term potentiation(LTP)in the spinal cord play an important role in the development of central sens
Objective Neuroimaging studies have indicated that patients suffering chronic pain showed structural and functional abnormalities in the brain.These observations have led to the notion that brain play
Gap junctions(GJ)play an important role in intercellular communication between adjacent cells.The protein expression,membrane cluster,subtype couple,pore selectivity and gating of GJs might be regulat
Auditory cortical neurons exhibit relatively large variation in their spiking responses to sound stimuli,reflected in the reliability of the response and the precision of the spike timing.The present
Objective: To study the distribute and nature of the lipid droplets within Hensens Cells(HCs)of guinea-pig Cotis organ; by Bodipy 493/503: one of the flurescent molecular probes for staining fats.
The olfactory system is important for mammals.Experimental approaches suggested that the glomeruli in the main olfactory bulb present a special map to odor stimuli.Although the same species share simi