1-(3-iodopropyl)-3-phenoxy benzene 5 was widely used in biological and pharmaceutical fields 1-2.Its a key intermediate of the preparation phosphonsulfonates such as 1 (BPH-652),developed by Bristol-M
Purposes.We have published a WEGA(Weighted Gaussian Algorithm)for molecular shape comparison,which is the engine of virtual drug screening.The algorithm is implemented in a single CPU system.Modern hi
A series of novel diarylpyrimidine with a halogen substituent on the methylene linker between wing I and the central pyrimidine were synthesized and evaluated for their anti-HIV activity in MT-4 cell