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5. Gene inactivation and non-meiotic allele introgression in livestock species using TALENs

Gene inactivation and non-meiotic allele introgression in livestock species using TALENs

来源 :The 11th transgenic Technology Meeting ISTT2013 ( 第十一届国际转基因技 | 被引量 : 0次 | 上传用户：wpe2727

【摘 要】

：

TALEN induced double strand breaks can be used for gene inactivation via repair by non-homologous end joining (NHEJ) or to stimulate homologous recombination (H

【作 者】

：

Scott C.Fahrenkrug 

【机 构】

：

Recombinetics,Minneapolis,Minnesota,USA

【出 处】

：

The 11th transgenic Technology Meeting ISTT2013 ( 第十一届国际转基因技

【发表日期】

：

2013年2期

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论文部分内容阅读

TALEN induced double strand breaks can be used for gene inactivation via repair by non-homologous end joining (NHEJ) or to stimulate homologous recombination (HR).HR can be used to introduce custom genetic modifications or to introgress naturally occurring alleles.

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