Novel fluorescent pesticide of praziquantel synthesis and application in pharmacological study of Cl

来源 :International Conference on Nanoscience & Technology,China 2 | 被引量 : 0次 | 上传用户:man168176
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  To investigate the interaction between praziquantel and Schistosoma japonicum cercariae, two praziquantel derivatives (PZQ-2 and PZQ-3) and one praziquantel fluorescent derivative (PZQ-5) have been synthesized and characterized by nuclear magnetic resonance spectroscopy (NMR) and MS spectra.Cytotoxicity of PZQ-2, PZQ-3 and PZQ-5 was measured by performing methyl thiazolyl tetrazolium (MTT) assay.
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