【摘 要】
：
In order to improve bioactivity ofdaidzein,we designed and synthesized a serial ofdaidzein naphthalene sulfonic acid ester derivatives using principles of k
【机 构】
：
JiangxiProvinceEngineeringResearchCenterofEcologicalChemicalIndustry,DepartmentofChemistryandEenviro
【出 处】
：
中国化学会第十三届全国有机合成化学学术研讨会
论文部分内容阅读
In order to improve bioactivity ofdaidzein,we designed and synthesized a serial ofdaidzein naphthalene sulfonic acid ester derivatives using principles of kinetophore transformation,and their structures were characterized by IR,MS,elemental analysis and 1H NMR spectral data.The synthesis process of key intermediate 2 was optimized from 5 aspects,such as time,temperature,the ratios of reactants,the ratios of solvent and catalyst,and the ratios of reactants and catalyst.These compounds could be further employed to inhibit the bioactivity of vascular smooth muscle cells.
其他文献
Diversity oriented synthesis (DOS) constitute one of the two major directions of modem organic synthesis.Electron deficient enamines such as enaminones and
Pd-catalyzed C-C cross-coupling reactions play a vital role in modern organic synthesis.Due to the high cost of Pd as well as environmental and product safe
Three-component coupling reactions of arylborons,carbon monoxide,and aryl halides,have been developed as powerful tools for the construction of biaryl and h
Pyrrole,as an important heterocycle,broadly exists in agrochemicals,natural products,synthetic intermediates and functional materials,ranging from compounds
Nitrones are not only widely recognized as important building blocks in the synthesis of various natural and biologically active compounds,but also used as
1989年,Jordan等人[1a]将阳离子型双茂基锆配合物成功地应用于催化吡啶邻位C(sp2)-H与烯烃的加成反应中,但是,该反应必须在有H2存在的条件下才能循环,在随后的几十年研究
Enantioselective phosphine organocatalysis has advanced rapidly over the past decades as a powerful tool for the preparation of numerous structurally divers
C-N bond formation reaction plays an important role in organic synthesis,which is often used in the synthesis of natural and synthetic bioactive compounds[1
N-aryl heterocycles have attracted increasing attention due to their wide applicability in biochemical,biological,medicinal and material sciences.1 The most
多环芳烃(又称纳米石墨烯或分子石墨烯)在有机光电材料领域具有潜在的重要用途,近年来其设计合成引人注目[1]。合成多环芳烃的一种重要策略是先构造出准平面多环芳烃碳架