TNFα-mediated MiR-136 and initiated IL-6-STAT3 signaling are involved in expansion of myeloid derive

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Chronic inflammation and tumor-associated factors are related to the increased accumulation of CD1lb+Gr-l+myeloid derived suppressor cells (MDSCs), which play a critical role in the development and progression of human diseases.But, the mechanism (s) of controlling expansion of MDSCs remains elusive.
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