Association of-394C > G and-420C > G polymorphisms in the RETN gene with T2DM and CHD and a ne

来源 :第八次全国医学遗传学学术会议(中华医学会2009年医学遗传学年会) | 被引量 : 0次 | 上传用户:yangbintian
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  Background Genetic variations of the human RETN gene are associated with metabolic phenotypes, including obesity, insulin sensitivity, diabetes and coronary heart disease.There are few studies of two gene variants,-394C > G and-420C > G, in Chinese population.Objective This study investigated the distribution of RETN gene single nucleotide polymorphisms (SNPs) in Chinese Han population and the association of the polymorphisms with type 2 diabetes mellitus (T2DM) and coronary heart disease (CHD).
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