Expansion of human mesenchymal stem cells in human platelet lysate as a substitute of fetal bovine s

来源 :2014天津国际干细胞论坛 | 被引量 : 0次 | 上传用户:nobank
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
Most clinical applications of human mesenchymal stromal cells (MSCs) for cell therapy,tissue engineering,regenerative medicine,and treatment of immune diseases require ex vivo expansion.
其他文献
We have previously showed that normal hematopoietic and progenitor stem cells (HSPC) were progressively suppressed during leukemogenesis (Hu et al.,2009),suggesting hematopoietic niche may play a role
会议
Cytopenia and delayed immune reconstitution with acute graft-versus-host disease (aGvHD) indicate a poor prognosis.However,how donor-derived cell hematopoiesis is impaired in aGvHD is not well underst
会议
Molecular mechanisms of the functional alteration of hematopoietic stem cells (HSCs) in leukemic environment attract intensive research interests.As known in previous researches,Maffand Egr3 are two i
会议
Disrupted hematopoiesis is a life-threatening complication after allogeneic hematopoietic stem cell transplantation (allo-HSCT) which,in most cases,is associated with graft-versus-host disease (GvHD).
会议
Current evidence suggests that the functional decline of adult stem cells contributes to the impaired organ homeostasis and functionality during aging.The mechanisms of stem cell aging are still poorl
会议
Human bone marrow contains a type of non-hematopoietic multipotent stem-like cells,termed mesenchymal stem cells (MSCs).MSCs represent an important cellular component of the bone marrow microenvironme
会议
Diamond-Blackfan anemia (DBA) is a class of human diseases linked to defective ribosome biogenesis that results in clinical phenotypes.Genetic mutations in ribosome protein (RP) genes lead to DBA phen
会议
Trithorax group (TrxG) proteins play critical roles in transcriptional activation by promoting methylation of histone H3 Lysine 4 (H3K4),but the precise functions of the individual TrxG members during
会议
Hematopoietic stem cell (HSC) is the source of all blood cells and its self-renewal capacity increases,while the reconstitution function compromises with age.Activation of tumor suppressor gene (TSG)
会议
Background Acute myeloid leukemia (AML)is generally regarded as a disorder of stem cells,known as leukemic initiating cells (LICs),which initiate the disease and contribute to relapses.
会议