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  5. β-Aminopropionitrile-induced aortic dissection model in C57B16J mice

β-Aminopropionitrile-induced aortic dissection model in C57B16J mice

来源 :中国生理学会基质生物学专业委员会成立大会暨第一次全国基质生物学学术会议 | 被引量 : 0次 | 上传用户：fanrend
【摘 要】
：
　　Aortic dissection (AD) is a life-threatening cardiovascular disease caused by progressive medial degeneration of the aortic wall.It is important to build a
【作 者】
：
Gao Yanxiang Liu Yuting Kong Wei Zheng Jingang 
【机 构】
：
DepartmentofCardiology,China-JapanFriendshipHospital,Beijing100029DepartmentofPhysiologyandPathophys
【出 处】
：
中国生理学会基质生物学专业委员会成立大会暨第一次全国基质生物学学术会议
【发表日期】
：
2016年3期
【关键词】
：
Aortic dissection β-aminopropionitrile animal model C57B1/6J 
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　　Aortic dissection (AD) is a life-threatening cardiovascular disease caused by progressive medial degeneration of the aortic wall.It is important to build a reproducible and durable small animal model to study the pathophysiology of AD.This study compared different β-aminopropionitrile (BAPN) or BAPN + angiotensin Ⅱ (Ang Ⅱ) treatment C57B1/6J to find the optimal BAPN model for AD in one study.
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