Cattle bone peptide pharmacodynamics research for osteoporosis prevention

来源 :中国生物化学与分子生物学会2016年全国学术会议 | 被引量 : 0次 | 上传用户:zcsq1987
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  OBJECTIVE To study the pharmacodynamics of cattle Bone peptide for osteoporosis;To study the prevention and treatment of osteoporosis for the menopause women.METHODS SD female rats were randomly grouped and were drenched after 2 weeks of ovariotomy.CT photography scaning,scanning electron microscope,the pathological section,bone stress test,the measurement of urine calcium content and the measurement of blood biochemical index shows the pharmacodynamics of cattle bone peptide.RESULTS The results of CT scaning demonstrated that the bone mineral density of cattle bone peptide group increased obviously.The results of scanning electron microscope and the pathological section showed that the number of bone trabecula of cattle bone peptide group increased markedly and the arrangement of structure was intenser.The content of phosphate,osteocalcin,and urinary calcium of cattle bone peptide group was lower than negative control(P<0.05).Conclusion The osteoporosis of SD rats can be prevented by cattle bone peptide drug.Menopause women maybe can prevent osteoporosis by taking health care products which contains cattle bone peptide.
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