How does lambda DNA find its unique integration site along an E.coli chromosome in order to establis

来源 :8th IUPAP International Conference on Biological Physics(第八届 | 被引量 : 0次 | 上传用户:shenyemaizui
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The search for specific sequences along genomic DNA is a key process in various biological contexts.Common to these is a search through a very large number of possible sequences on long genomes.How can specific target sequences be located with high efficiency, within physiologically relevant times? We addressed this question for viral integration, a fundamental mechanism of horizontal gene transfer driving prokaryotic evolution, using the infection of E.
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