Preclinical and Clinical Pharmacokinetics of the XIENCE V(R) Everolimus Eluting Coronary Stent Syste

来源 :BITs 2rd Annual World Cancer Congress of Cardiology-2010(201 | 被引量 : 0次 | 上传用户:zhangqiang
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  Drug-eluting stents (DES) are widely used for the treatment of coronary artery disease with benefit of reduced restenosis compared to bare metal stents.The XIENCE V(R) Everolimus Eluting Coronary Stent System is a second generation DES system for better deliverability while maintaining safety and efficacy profiles.Everolimus delivered by the XIENCE V(R) stent is in the family of sirolimus which exerts its anti-proliferation of vascular smooth muscle cells through blocking the mTOR (mammalian target ofrapamycin) function.
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