我们对DISC1 基因点突变小鼠(L100P)情感和认知功能进行分析，并考察了常用抗精神病及抗抑郁药物对这些功能障碍的改善作用.实验选用DISC1-L100P 纯合子小鼠和同窝野生型小
Elevated iron accumulation and increased divalent metal transporter 1 (DMT1) expression have been reported in the substantia nigra (SN) of Parkinsons diseas
DNA methylation catalyzed by DNA methyltransferases (dnmt1,dnmt3a and dnmt3b) is considered to play vital roles in learning and memory.Our previous studies
小麦(Triticum aestivum L.)是世界上最重要的粮食作物之一,改善其营养品质是小麦遗传育种的重要研究方向。类胡萝卜素含量是衡量小麦营养品质的重要指标之一。类胡萝卜素是
Ginsenoside Rg1 is the main pharmacologically active compound of ginseng.Many studies have shown that Rg1 possess a variety of beneficial effects on human h
寻常性鱼鳞病(Ichthyosis Vulgaris,Ⅳ)是遗传性皮肤病的一种常见类型,国际上报道其发病率在1:250至1:5300之间,中国人群发病率为0.23%。寻常性鱼鳞病通常在出生后一年内开始起病。其临床特征包括皮肤干燥,病人的四肢伸侧外表皮产生白色的鳞屑,躯干部也偶有出现,还包括掌跖线状皲裂和掌纹加深,遗传性过敏症和不耐热性。寻常性鱼鳞病遗传方式复杂,以常染色体显性遗传多见,存在遗传异质
Dnmt1 and Dnmt3a are important DNA methyltransferases that are expressed in postmitotic neurons.Our previous studies showed that conditional double knock-ou
Nesfatin-1,a newly discovered satiety molecule which reduces feeding behavior,has been recognized as a unique regulatory neuropeptide with its multiple role
Cerebellar cortex receives sensory information from climbing fiber and mossy fiber-granule cell pathways,and generates motor-related outputs according to in
目前，百合(Lilium hybridum）种球的培育有珠芽培养法、小鳞茎培育法、鳞片扦插培育法和种子培育法等。但普遍存在种球退化、繁殖系数低、造成栽培效果较差等问题。另外杂交育种