Mindfulness meditation has been incorporated into stress reduction programs and psychotherapy interventions due to the promising research results on the effectiveness of mindfulness.However, the neurobiolo gical understanding of mindfulness is still in early stage of investigation.Aimed at understanding the neurological mechanism of mindfulness, this research reviews relevant neurobiological experiments on mindfulness meditation and provides summary of brain regions and activity responsive to mindfulness practice.Implications and suggestions for future research on neurological studies of mindfulness are discussed.