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5. Gastric Lgr5+ stem cells are the cellular origin of invasive intestinal-type gastric cancer in mice

Gastric Lgr5+ stem cells are the cellular origin of invasive intestinal-type gastric cancer in mice

来源 :第三届全国发育生物学大会 | 被引量 : 0次 | 上传用户：ghostwazy

【摘 要】

：

The cellular origin of gastric cancer remains elusive.Leucine-rich repeat-containing G-protein-coupled receptor 5 (Lgr5) is the first identified marker of gastric stem cells.However,the role of Lgr5+

【作 者】

：

Xiu-Bin Li Guan Yang Liang Zhu Yu-Ling Tang Chong Zhang Xiao Yang Yan Teng 

【机 构】

：

State Key Laboratory of Proteomics, Genetic Laboratory of Development and Disease, Institute of Biot

【出 处】

：

第三届全国发育生物学大会

【发表日期】

：

2016年8期

【关键词】

：

gastric tumorigenesis gastric stem cell Lgr5 lineage tracing 

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　　The cellular origin of gastric cancer remains elusive.Leucine-rich repeat-containing G-protein-coupled receptor 5 (Lgr5) is the first identified marker of gastric stem cells.However,the role of Lgr5+ stem ceils in driving malignant gastric cancer is not fully validated.

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