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Objective Although intravenous adenosine is recommended for acute vasodilator testing in patients with pulmonary hypertension, the long-term outcomes in acute responders treated with calcium channel blockers (CCBs) who are identified by adenosine remain unknown.In this study, the value of adenosine for identifying long-term responders to CCBs was investigated in patients with idiopathic pulmonary arterial hypertension (IPAH).